Orlistat is a prescription medicine commonly used to help manage obesity and support weight loss. It works by reducing the amount of fat your body absorbs from food in the stomach and intestines, which helps lower overall calorie intake.Orlistat 120 mg is usually taken with meals that contain fat and is most effective when combined with a balanced low-calorie diet and regular exercise. Common brand versions include Xenical and several generic alternatives. Some people may experience digestive side effects such as oily stools, stomach discomfort, or frequent bowel movements, especially after high-fat meals. It should be used under medical guidance for safe and effective weight management.